Neurology & Neuroscience

Background: Tuberculosis is one of the communicable disease that caused by Mycobacterium tuberculosis (MTB), it could damage multiple organs in which the most common is lung. However, if it’s left untreated or the treatment is not appropriate, TB could make harmful complication such as death. Among 1-2% of all the TB cases is manifested in bone especially vertebrae known as Spondilytis tuberculosis or known commonly as Pott’s Disease (PD). To prevent the complication of this disease, we have to detect early foci of infection from PD, and prompt treatment could be done earlier. Examination as sputum specimen is the routine check for analyzing Mycobacterium tuberculosis. According to the case report from George et al in 2016, PD patient was diagnosed by using urine sample in GeneXpert method. Meanwhile, there is no publication of PCR method using urine as a sample of PD patient yet.

 

Aim: To know, is the urine samples could detect MTB from Spondilytis tuberculosis patient using PCR method in September-October 2017 period in RS. Wahidin Sudirohusodo, Makassar, Sulawesi Selatan.

Method: This research is descriptive observational. We conduct the urine samples could detect MTB from Spondilytis tuberculosis patient using PCR method in September-Oktober 2017 period in RS. Wahidin Sudirohusodo, Makassar, Indonesia.

 

Result: According the research time from September-October 2017, we get 10 samples. Each of sample was analyzed using PCR method and there are 3 samples are positive in 441 bp band (p = 0.350).

Conclusion: Urine sample in which using PCR method can be the tool of diagnosis in Spondilytis tuberculosis.